Clinicopathology of dementias.

Clinicopathology and prognosis of mucinous gastric carcinoma.

BACKGROUND/AIMS Mucinous gastric carcinoma (MGC) is a rare histopathological type of gastric carcinoma, for which the clinicopathological features and prognosis remain controversial. To clarify the clinical significance of mucinous histological type in gastric cancer, we studied clinicopathological characteristics of MGC tumors and prognosis of patients. METHODOLOGY Forty-one patients with MG...

Genetics of the dementias.

While the majority of dementias are sporadic, many diseases causing dementia can also occur on a familial basis. Some of these show an autosomal or sex linked inheritance. In others, certain genes are not directly causative, but are major risk factors. Some dementias may be definitively diagnosed in vivo or prenatally using genetic testing. The discovery of causative genes has also led to the d...

The dementias of schizophrenia

Cases of "adolescent insanity" were known to Kraepelin's forerunners and lay at the core of his concept of dementia præcox. In the post-neuroleptic era it became clear that dementia may also occur in schizophrenia as a fully reversible state depending on psychopathological status. In the present review we discuss the validity of applying the concept of dementia to schizophrenia. We concur with ...

Neuroimaging of dementias.

Biochemical aspects of dementias

Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, and prion diseases are age-related neurodegenerative disorders associated with a progressive decline of cognitive brain functions. Due to the increase in prevalence rates, and the rising costs associated with clinical and social care, treatments designed to prevent or reverse these diseases are urgently needed. The most co...